AS AND NR-AXSPA IN WOMEN VS MEN
Currently, more men are diagnosed with ankylosing spondylitis (AS), and more women are diagnosed with non-radiographic axial spondyloarthritis (nr-axSpA), but numbers may be closer than originally thought. Recent studies suggest important differences in how women and men experience axial spondyloarthritis (axSpA), which includes both AS and nr-axSpA.
Compared with men,
WOMEN WITH AS OR NR-AXSPA MAY HAVE:
- Longer delay in diagnosis
- Slower disease progression
- More pain in the neck and peripheral (arm and leg) joints
- More pain, stiffness, and inflammation at the same level
- Less damage to bones and joints visible on an X-ray
- Higher frequency of conditions beyond the joints, like enthesitis, psoriasis, and inflammatory bowel disease
- Poorer quality of life
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1. Baraliakos X, Braun J. Non-radiographic axial spondyloarthritis and ankylosing spondylitis: what are the similarities and differences? RMD Open. 2015;1(suppl 1):e000053. doi:10.1136/rmdopen-2015-000053 2. Most common symptoms. Spondylitis Association of America. Accessed September 8, 2022. https://spondylitis.org/about-spondylitis/overview-of-spondyloarthritis/ankylosing-spondylitis/symptoms/ 3. Rusman T, van Collenhoven RF, van der Horst-Bruinsma. Gender differences in axial spondyloarthritis: women are not so lucky. Curr Rheumatol Rep. 2018;20(6):35. doi:10.1007/s11926-018-0744-2